Friday, December 27, 2019

How Many Moles of C Atoms Are in 1 mol of Sucrose

One of the first questions youll encounter when working with moles will ask you to determine the relationship between number of atoms in a compound and the number of moles (mol). (To refresh your memory, the mole is the SI unit identifying the number of particles in a given amount of matter.) For example, how many moles of carbon (C) atoms are in 1 mole of table sugar (sucrose)? The chemical formula of sucrose is C12H22O11. When you are given a chemical formula, each one- or two-letter symbol stands for an element. C is carbon, H is hydrogen, and O is oxygen. The subscripts following each element symbol indicate the number of atoms of each element in the molecule. So, 1 mole of sucrose contains 12 moles of carbon atoms, 22 moles of hydrogen atoms, and 11 moles of oxygen atoms. When you are talking about 1 mole of sucrose, its the same as saying 1 mole of sucrose atoms, so there are Avogadros number of atoms in one mole of sucrose (or carbon, or anything measured in moles). There are 12 moles of C atoms in 1 mole of sucrose.

Thursday, December 19, 2019

Usage Of Restriction Enzymes Of Dna Fingerprinting

Usage of Restriction Enzymes in DNA Fingerprinting Analysis Jaclyn Napoli October 30, 2014 Cellular Processes Lab BSC 2010L.905 Lab Partner: Jessi Grillo Material and Methods To start off the experiment, 4 microtest tubes were labeled reaction tube 1 through 4. Using a micropipette, 10 microliters, ul, of Enzyme Reaction Buffer was dispensed into each of the 4 labeled reaction tubes. In reaction tubes 1 and 2, 15 ul of suspect 1’s DNA was added. Reaction tube 1 had 15 ul of Enzyme 1 added to it, and reaction tube 2 had 15 ul of Enzyme 2 added to it. 15 ul of suspect 2’s DNA as added to reaction tubes 3 and 4. In reaction tube 3, 15 ul of Enzyme 1 was added. Then, in reaction tube 4, 15 ul of Enzyme 2 was added. Finally, 2 more microtest tubes were labeled as crime scene samples. The samples contained DNA from the crime scene and each the tubes had either Enzyme 1 or Enzyme 2 added to it. The microtest tubes were then capped and tapped lightly to allow the ingredients to mix. The reaction tubes were submerged in a 37 °C, ice water, for 45 minutes. Once complete, 5 ul of 10x gel loading solution was added to all 6 of the microtest tubes. Ref er to Table 1 for a quick overview. Table 1 Summary for Restriction Enzyme Digestion Process. While the tubes were being cooled, a casting gel was made. The cast was made by combining 0.5 grams, g, of agarose and 50 milliliters, ml, of TBE buffer into a 250 ml flask. The TA added ethidium bromide to the solution to allowShow MoreRelatedCrime Scene Samples With Gel Electrophoresis1181 Words   |  5 PagesComparing Suspect DNA to Crime Scene Samples with Gel Electrophoresis Christopher Davis Lab Partners: Jessica Roubert and Aishat Alimi TA: Tam-Anh Phan BSC 2010L Section: 033 November 1, 2014 Materials and Methods Restriction Enzyme Digest and Preparation of the DNA Samples Four microcentrifuge tubes were placed in a rack, labeled and numbered, in order to identify the group and the DNA/restriction enzyme that it held. Each of the tubes initially received 10 microliters of reaction bufferRead MoreDna Fingerprinting : A Method Of Dna Analysis Used By Forensic Scientists2462 Words   |  10 PagesRoughly speaking, DNA Fingerprinting is a method of DNA analysis used by Forensic Scientists to help solve crimes. This technique was first discovered by Professor Alec Jeffreys of the University of Leicester in 1984, when he found that DNA varies in each human being, and makes us unique. DNA could be retrieved from hair, blood and saliva amongst other things such as skin and semen. DNA fingerprinting works on the basis that each individual s DNA structure – also known as the genetic make-up ofRead MoreSolving Cases with Forensic DNA Analysis975 Words   |  4 PagesForensic DNA analysis is still a relatively new method that has been used to solve cases such as crimes and paternity tests. This method of forensic evaluation is examined by using genetic material, DNA, an acronym for deoxyribonucleic acid. Although each individual’s DNA differs from someone else’s, with the exception of identical twins, around 99.9% of DNA is the same in each person (The FBI DNA Laboratory). Therefore, in order to identify the genetic profile of the individual being analyzedRead MorePaternity Testing And Paternity Test1546 Words   |  7 Pagesalso use in court order for cases, like the mother trying to get child support or if the father asking for verification that the child is indeed their own. This test began on a blood typing testing, but later on Alec Jeffrey’s discovered the DNA fingerprinting, which started the use of paternity test in 1988. The paternity test called ABO is one the most popular test done. The abbreviations stands for A (Allele), B (allele for Codominant), and O for (allele Recessive). Allele’s are types of genesRead MoreHow Technology Has Impacted Criminal Investigation Essay2211 Words   |  9 Pagesatmosphere and reduces the rate of crime. Technology is the usage and knowledge of techniques or is systems of these things. Usage of technology in the criminal justice system is not new but more apparent today. Technology in criminal justice will continue to challenge us to think about how we turn information into knowledge. Due to new technology, criminal investigations are able to maintain and improve their processes. Forensic science, DNA, other and future technology has all had a tremendous impactRead MoreBiometric Security System : Amity School Of Engineering3521 Words   |  15 PagesDEVELOPMENT IN SCIENCE AND TECHNOLOGY †¢ BENEFITS ïÆ' ¼ INTRODUCTION †¢ DETAILED OVERVIEW ïÆ' ¼ HISTORY ïÆ' ¼ TYPES OF METHODS USED FOR SECURITY †¢ TRADITIONAL METHODS ï  ¶ PINCODE SECURITY ï  ¶ PASSWORD SECURITY †¢ MODERN METHODS ï  ¶ PHYSIOLOGICAL METHODS †¢ RETINAL SCAN †¢ FINGERPRINTING †¢ DNA †¢ IRIS ï  ¶ BEHAVIORAL METHODS †¢ VOICE/PITCH †¢ SIGNATURE ïÆ' ¼ ADVANTAGES ïÆ' ¼ APPLICATIONS ïÆ' ¼ CONCLUSION ïÆ' ¼ REFERENCES ABSTRACT OBJECTIVE: OUR MAIN OBJECTIVE IS TO STUDY THE MEANING AND TYPES OF BIOMETRIC SYSTEMS THAT ARE USED TO VERIFY THE AUTHENTICATION

Wednesday, December 11, 2019

Brainstorming and Ideas Essay Sample free essay sample

What is Brainstorming?* Brainstorming is a tool used by squads to convey out the thoughts of each person and show them in an orderly manner to the remainder of the squad. * Brainstorming creates new thoughts. solves jobs. motivates and develops squads. Brainstorming motivates because it involves members of a squad in bigger direction issues. and it gets a squad working together. However. brainstorming is non merely a random activity. Brainstorming demands to be structured and it follows brainstorming regulations. The brainstorming procedure is described below. for which you will necessitate a flip-chart or alternate. * This is important as Brainstorming demands to affect the squad. which means that everyone must be able to see what’s go oning. Brainstorming places a important load on the facilitator to pull off the procedure. people’s engagement and sensitivenesss. and so to pull off the follow up actions. Use Brainstorming good and you will see first-class consequences in bettering the organisation. public presentation. and developing the squad. Why should a squad make Brainstorming? Brainstorming helps a squad interruption free of old and uneffective thoughts. This free-wheeling technique for bring forthing thoughts may bring forth some that seem crazy. but it can take to new and original solutions to jobs. Some of the specific benefits of Brainstorming: * Encourages creativeness. It expands your thought to include all facets of a job or a solution. You can place a broad scope of options. * Quickly produces a big figure of thoughts. By promoting people to offer whatever thoughts come to mind. it helps groups develop many thoughts rapidly. * Equalizes engagement by all squad members. It provides anon-judgmental environment that encourages everyone to offer thoughts. All thoughts are recorded. * Stephen fosters a sense of ownership. Having all members actively take part in the Brainstorming procedure Fosters a sense of ownership in the subject discussed and in the resulting activities. When the people on a squad contribute personally to the way of a determination. they are more likely to back up it. * Provides input to other tools. You may desire to affinitize the brainstormed thoughts. And. if appropriate. you can work with the squad to cut down the figure of thoughts by Multi-voting. Brainstorming is utile when you want to bring forth a big figure of thoughts about issues to undertake. possible causes of jobs. attacks to utilize. or actions to take. What are the land regulations for Brainstorming?For all participants to bask a originative and productive Brainstorming experience. the facilitator needs to reexamine and acquire team members’ buy-in on the land regulations for the session. These are the regulations: * Active engagement by all squad members. Everyone expresses his or her thoughts. even if they seem silly or far out. * No discussion—criticisms. regards. or other comments—during the insight. * Build on thoughts generated by other squad members. * All thoughts written precisely as presented and displayed where everyone can see them. * Set a clip bound.* Clarify thoughts. After the insight. travel over the list to do certain that all squad members understand the thoughts. Remember that you are merely clear uping the thoughts. non doing judgements about them. * Combine thoughts. See whether two or more thoughts that appear to be the same can be combined. How is a Brainstorming session conducted? The recommended sequence for carry oning Brainstorming and some suggestions for carry oning the session efficaciously are provided below: * Review the regulations for Brainstorming. Describe how this session will be conducted by traveling over the points below. * Set a clip bound for Brainstorming. delegate a timer and informations recording equipment. and get down the clock. Brainstorming should be a rapid coevals of thoughts. so make it rapidly ; 5-15 proceedingss works good. If the clip bound has expired and thoughts are still being generated. you can widen the clip bound at five-minute intervals. * State the subject to be brainstormed in the signifier of a inquiry. Write it down and post it where everyone can mention to it. Guarantee that everyone understands it. * Collect everyone’s thoughts. After leting a few proceedingss for the participants to believe about the inquiry. inquire them to give their thoughts. Establish either a structured or unstructured format for namin g out thoughts: * Structured: The facilitator establishes a rotary motion that enables each individual in the group to lend an thought in bend. Any single who is non ready with an thought when his or her bend comes can go through until the following unit of ammunition. when he or she may offer an thought or base on balls once more. * Unstructured: Team members call out thoughts as they come to mind. This method calls for close monitoring by the facilitator to implement the land regulations and guarantee that all squad members have a opportunity to take part. * Record thought on a chart battalion as they are called out. or cod thoughts written by squad members on Post-Its. Expose the thoughts where everyone can see them. Having the words seeable to everyone at the same clip avoids misunderstanding and duplicate and helps excite originative thought by other squad members. * When entering thoughts. guarantee that they are written down precisely as spoken by the squad member. Don’t interpret. * Clarify each thought after all thoughts have been presented. to guarantee that all members have the same apprehension of it. Indicating to each thought on the chart battalion in bend. inquire the participants whether they have any inquiries about its significance. You may hold to inquire the subscriber to explicate the thought in a different manner. * Eliminate duplicates. If two or mo re thoughts appear to intend the same thing. you should seek to unite them or extinguish the extras. Before you can wrap the similar thoughts into a individual point or extinguish any points on the list. all of those who contributed the similar thoughts must hold that they mean the same thing. Otherwise. they remain as separate points. Brainstorming Techniques * Clustering1. Get down with the chief subject of your essay. Write that word in the centre of your paper. 2. Write down any sub-topics that are connected to that chief subject. Draw arrows to the sub-topics from the chief subject. 3. If you have new thoughts. connect those words to the appropriate sub-topic. * Listing/Bulleting 1. Make a list of terms/ideas/concepts about the subject. 2. Create multiple lists depending on the intent.* Making a CubeSide One: Describe the subject.Side Two: Compare the subject.Side Three: Associate the subject.Side Four: Analyze the subject.Side Five: Use the subject.Side Six: Argue for or against the subject.* Venn Diagram1. Pull two circles that connect. like this: 2. List two subjects above the circles.3. Brainstorm about the subjects – what do they hold in common and what is alone about each one. * Tree Diagram* This diagram has a cardinal thought to which you add subdivisions that focus on inside informations. * Act like a Journalist* It answers the inquiries on what. where. when. why and how * T-Diagram* Using a T form. name a class that you want to compare or contrast about a specific subject or subjects. Make this for a assortment of classs. The Philosophy of BrainstormingBy forcing past the obvious. brainstorming has penetrated the doctrine of the normative and gave birth to a whole new doctrine. the doctrine of spontaneousness. Truly being self-generated consequences to being more originative. â€Å"Brainstorming is a originative thought procedure that can be undertaken as a group activity. though there are a few instances where persons besides use same technique to bring forth wide. diverse and originative thoughts particularly targeted towards work outing a particular job. There are several fluctuations of this technique but across all. there are a few cardinal similarities. One of the supposed cardinal feature of brainstorming is the spontaneousness of the thought coevals procedure. It would look like the more self-generated the brainstorming session is. the more legitimate it is. the more consequences or originative thoughts we believe we can bring forth. It is this cardinal thought that I truly want to dispute. The chief idea behind this spontaneousness of thought coevals is that it is assumed that when thoughts are self-generated. they are fresh. originative and uninhibited by bing believing. pre-conceived thoughts or antecedently tested solutions. As the brainstorming procedure is normally deployed where the job is intractable. new or when the state of affairs has grown to new dimensions. it is hence thought that the ‘spontaneity’ helps unlock new. originative and breakthrough thoughts. However. when you truly halt and believe about it. where and when do you truly acquire your best thoughts? Where do you acquire your most originative and advanced ideas? Does that co-occur with a certain clip of the twenty-four hours and is it when you do a certain activity? Does music or doodling aid? Make you necessitate to be by yourself to be most originative? Knocking each other’s ideas ; this is non even acceptable. if you go by the purist position of brainstorming. So if brainsto rming does non enable the coevals of discovery thoughts and thought. so where and how do we bring forth and acquire our best thoughts from? I have asked this inquiry to quite a few people and professionals for that affair and they were rather consentaneous that originative thoughts rarely happened in the office. It was when they were driving. kiping. jogging. tick overing off at Television. taking a shower or a lazy bath or when reading a book in the ‘other’ little room. holding dinner with friends. etc. That is why a few of the world’s greatest thoughts in the last century started in eating houses on paper serviettes. Not surprisingly. it was when people were relaxed. at easiness. non believing about work or that job state of affairs that they were the most originative. Furthermore. it was frequently in the forenoon or tardily in the eventides. but seldom in the afternoon – which is normally when we are at work. brainstorming. Surveies and findings about how the encephalon works corroborates above responses to my inquiry about when people feel they are the most originative and when they had br eakthrough thoughts and ideas in the yesteryear. So. if this is true and research proves it is. why do we still carry on as if a brainstorming session will really make some white infinite for us? What organisations and persons who know and are smart about this bash is that instead than hold a brainstorming session where we recycle thoughts. they really province the job yearss and hebdomads in progress. so that their staff in their ain manner and clip of being originative. will come into the room on that twenty-four hours with clear thought and originative thoughts on how to travel things frontward. † -Business Day. â€Å"The Wisdom of Brainstorming the Contrarian View† by Ted I. Theodore. hypertext transfer protocol: //businessdayonline. com/NG/index. php/work/35370-the-wisdom-of-brainstorming-a-contrarian-view Being originative will ever be a piece on the brainstorming doctrine. for brainstorming is non merely the coevals of thoughts but the coevals of the best thoughts. Harmonizing to Shaina Rozen’s article. Creativity Happens When You Throw out All Ideas. â€Å"We employ this â€Å"reach deeper† brainstorming doctrine in our work and have found that some of the best thoughts are the 1s that come up after we’ve exhausted all our options. In fact. we’ll frequently walk off from a long brainstorming session and come back the following twenty-four hours to rest our heads. digest some of the thoughts. and come back with a clear caput. Albert Einstein said. â€Å"Insanity is making the same thing over and over once more and anticipating the same consequences. † Making the same old brainstorming may give an astonishing thought one time in a piece. but more frequently than non. it’s merely traveling to bring forth second-rate consequences for your client. However. when you spice up your everyday and push yesteryear the obvious. you merely might blow them off. hypertext transfer protocol: //fortyagency. com/insights/creativity-happens-when-you-throw-out-the-obvious-ideas â€Å"The student-brainstormer portions one major feature with the student- bullshitter: she typically has non reflected profoundly about the philosophical issue under treatment. But. unlike the bullshitter. she is eager to research it by dialoging with others. This is because she is personally related to the subject. She takes it to be a unrecorded one ; it means something to her as an person. † – Kerry S. Walters. On Bullshitting and Brainstorming. 1988. BRAINSTORMING TIPS AND TECHNIQUESMind mapsMind function is the easiest and most popular signifier of brainstorming. They’re particularly effectual if you’re brainstorming on your ain. A head map is a graphical representation of all your thoughts linked to and arranged around one cardinal thought. job or subject. There are no regulations to it apart from jotting down everything that comes in your caput. Your head map can be hierarchal or in a tree subdivision format. You can either make mind map on a paper or utilize an on-line plan like Mind Meister which lets you salvage. import and export your head maps and comes with a free version every bit good. Brain mopess Brain mopess are the most fun. Take a piece of paper or open up your word processor and get down composing everything that comes to mind. There’s no regulation stating it has to be related to the undertaking. If you’re brainstorming logo thoughts for a client and happen yourself believing about tiffin. observe down what you want to hold. Trust me. it’s much more productive this manner. Otherwise. you’ll be stuck seeking to come up with Sons while your oral cavity is irrigating as you’re believing about nutrient. Collaboration If you find yourself stuck for thoughts. talk to person and ask for them on board for the undertaking. Get them to brainstorm with you and compare notes. More frequently than non. your brainstorming spouse will pick up something you might hold missed. happen a correlativity or come up with a alone angle that you wouldn’t hold thought of on your ain. If you don’t want to spouse up on the undertaking. that’s mulct. You can still acquire them to join forces with you for brainstorming every bit long as you return the favor. Change by reversal brainstorming Rearward brainstorming can work in two ways. The first is to visualise the consequence you want to accomplish and so work your manner back to the start. For illustration. if you want to compose a web log station. so depending on how you write. your contrary believing timeline will look something like: †¢Respond to remarks †¢Publish station†¢Format station†¢Write station†¢Create an lineation of the station†¢Write rubricThis technique helps you concentrate on countries that you may take for granted and high spots anything that you might hold missed. In the illustration above. you might recognize that you didn’t pay attending to the data format of the station and now know that you need to make The 2nd manner is to inquire yourself the opposite inquiry of what you’re seeking to accomplish. First. inquire yourself ‘How do I accomplish these consequences? ’ and so inquire ‘How make I accomplish the exact antonym? ’ Let’s take this web log station for illustration. When brainstorming the thoughts for this station. I wanted to do this station exceeding. So I asked myself ‘How can I do this station amazing? ’ I drew up a space. I spent an hr looking at my lineation for this station seeking to calculate out how to do it astonis hing. Then I decided to inquire myself ‘How can I do this station mediocre? ’ The reply was gazing me right in the face – for both this inquiry and the one above. I could do this station mediocre by merely explicating the tips and techniques for brainstorming and non giving any illustrations and non demoing how to utilize these tips. Group Sessionss Group Sessionss are great for acquiring past thoughts that have you stuck. If you’re stuck at a peculiar subdivision of your undertaking. a group brainstorming session can be your ticket to lucidity. The people in your group conveying their ain experience and cognition that will assist you happen thoughts for work outing your job. It’s non necessary for the group members to be from the same field as you. Equally long as they have a fundamental apprehension of what you’re seeking to work out. their thoughts can be priceless. Sometimes. even input from person who has no thought what you’re speaking about can assist. Promote them to inquire inquiries and suggest any thought that comes to their caput – even if it seems silly. Having a novice’s position on your job may merely be what you need to happen a solution. Ask Questions Asking inquiries is a great manner to come up with thoughts and replies to your jobs. Use prompters like what. where. who. when. and how. Suppose you’re making a web site for a tooth doctor. inquire ‘Who is the client? ’ The reply will be. people who have jobs with their dentitions. Next. ask. ‘What sort of jobs do they hold? To which you’ll reply ‘Toothaches. pits. dental plates. etc’ and so on until you have all information you need. Put A Time Limit Puting a clip bound is a great technique if you’re pressed for clip or haven’t been able to brainstorm successfully. It forces you to concentrate and come up with every bit many thoughts as it can in the given clip. The continuance of the clip bound depends on you. The bound has to be short plenty to instil a sense of urgency but long plenty to let you to enter all your thoughts. If you’re seeking this technique for the first clip. get down with 10 proceedingss. For bigger undertakings. interrupt your undertakings down in little balls and so brainstorm them one by one. This manner you won’t experience overwhelmed by the sheer size of the undertaking. SWOT Analysis A SWOT analysis is an analysis of your project’s strengths. failings. chances and menaces. Making a SWOT analysis will give you a clear thought of what you have. what you need. what you can capitalise on and what you need to better. Individual BrainstormingIndividual brainstorming puts you in complete control of the originative procedure. and that means you are entirely responsible for any and all consequences. This makes single brainstorming a welcome challenge for some. and a beginning of concern for others. The Upside of Individual BrainstormingWhile single brainstorming may non let you take advantage of the accrued experience of other members of your squad. it will supply you with the freedom to show thoughts without fright of ridicule or rejection. An thought that you may hold been hesitating to convey up in a group brainstorming session may come to fruition during the single brainstorming procedure. and that individual thought may be the 1 that makes the procedure a success. In add-on to supplying you with added personal freedom. single brainstorming besides forces you to delve into the brainstorming procedure and give yourself over to it wholly. When an single insights with a group of people. he or she may be inclined to let others to take the procedure. When single brainstorming is being conducted. there is no 1 else to trust on. which motivates the brainstormer to bring forth thoughts and constructs on their ain. While there is much to be said for group brainstorming. single brainstorming is a procedure that shouldn’t be overlooked. There is much to be said for holding the freedom to pull off your originative procedure without the influence of sentiments. thoughts or self-importances of others. Group BrainstormingWhen it works. group brainstorming can be really effectual for conveying the full experience and creativeness of all members of the group to bear on an issue. When single group members get stuck with an thought. another member’s creativeness and experience can take the thought to the following phase. Group brainstorming can therefore develop thoughts in more deepness than single brainstorming. The Upside of Group BrainstormingAs a regulation. people by and large have originative boundaries that they stay within. Oftentimes. these boundaries are referred to as a â€Å"box† and when one begins to believe â€Å"outside of the box† the originative procedure can truly take off. Group brainstorming helps the members of the brainstorming squad believe outside of their boxes. opening originative doors for each member of the brainstorming squad. Another advantage of group brainstorming is that it helps everyone involved to experience that they’ve contributed to the terminal solution. and it reminds people that other people have originative thoughts to offer. Brainstorming in a group can be hazardous for persons. Valuable but unusual suggestions may look stupe at first sight. Because of this. you need to chair Sessionss tightly so that thoughts are non crushed. and so that the usual issues with group problem-solving don’t knee creativeness. Making a diver se brainstorming squad allows for multiple fonts of cognition and experience for the group brainstorming squad to pull from. Group brainstorming can besides move as a team-building exercising by doing certain all members of the squad show their sentiments and lend their thoughts. | | Approachs to Brainstorming * The Stepladder Technique- This improves the part of quieter members of the group. by presenting thoughts one individual at a clip. The Stepladder Technique is a simple tool that manages how members enter the decision-making group. It encourages all members to lend on an single degree before being influenced by anyone else. This consequences in a wider assortment of thoughts. it prevents people from â€Å"hiding† within the group. and it helps people avoid being â€Å"stepped on† or overpowered by stronger. louder group members. * Brainwriting – Brainwriting uses a written attack to brainstorming to bring forth and develop thoughts. This helps you get thoughts from all persons. and develop these thoughts in deepness. It is similar to brainstorming – they’re both methods for bring forthing thoughts and solutions for a job nevertheless it gives everyone equal chance to take part. and it enables all group members to believe without any ‘blocking. ’

Tuesday, December 3, 2019

Robert Lee Essays (614 words) - Randolph Family Of Virginia

Robert Lee Robert Edward Lee was born on January 19th, 1807 in Stratford, Virginia. Robert's father was thrown in debtors jail many times for not paying on time. He was introduced to war early in his life; his brother Sydney had shown him a cannon ball and told him about the revolution. Mrs. Lee's stepson was old enough to claim the mansion where they lived that his dead mother had gave to him in his will. The Lee's left to live in Alexandria. Lee was brought up in a Christian family. When Lee was 18, he went to West Point. There were only 6,000 other men in the entire army. Later that year, Lee said goodbye to his mother and took a stagecoach from Virginia to New York. At the end of his first year at West Point, he was appointed Staff Sergeant. When he was twenty-two, he took his money that he earned; $103.58 in cash and he started a home. On July 26, 1829, Lee's mother died. Robert was at her bed when she died. Then on June 30, 1831 Lee married Mary Curtis. On September 16, 1832, Mary gave birth to George Washington Curtis Lee. Then in 1835 they had their second child, Mary Curtis. Mrs. Lee was put on bed-rest for many months due to illness. They had five more children: William Henry Fitzgerald, Annie, Agnes, Robert and last Mildred. When he was home, they all attended episcopal Church where he was raised. On May 13, 1846 the United States declared was on their southern neighbor. When Lee was 39, he headed for Mexico. Lee's will said that he was worth about $38,750 with few depts. He only had few slaves: Nancy and her children. And they were to be freed "soon as it can be done to their advantage and that of others. On Christmas, Lee wrote to his wife that he hoped this woul.d be the last time he would be away from her. While they were at war, even though is was hard, he attended church. He returned on June 29, 1843. On September 1, 1852 he was appointed to superintenent of the military acadamy where he had graduated. In 1853, a distressing message reached Lee: Mrs. Curtis had died unexpectedly. The death made him do something he had never thought of doing. He wanted to be confined to the church. It was gunners at Charlestown Harbor who forced Robert E. Lee to make the tough decisions in his life. On April 12, the United States, as the union fired upon by Confederate gunners. The civil war began with the first cannon roar at Fort Sumpter. The north had more of an advantage because they have all of the military supplies and factories. The south was a land of farmers without military supplies and hardly any money to buy them. Then one day when Lee was in hid hotel, he had a visitor. He read a report of the supplies coming into Richmond. 60,00 small arms, and 54,00 flintlocks. I July 21, 1861 they received a telegram that the south had won the first major battle of the Civil War. One evening Lee looked up to see a soldier salute. "Major Rooney Lee was fired upon by Union pickets, Sir, near Cheat Mountain. His companion, Colonel Washington, died instantly. Union pickets put three Minie ball through his body." Then Lee's face lost it's color. "Your son's mount was shot from under him. Major Lee escaped on Washington's horse, sir." Lee sighed in relief. Washington's death hit Lee. He was a good friend of the family. Lee had been involved in the war for the whole time that it was going on. He had many battles, and he was fighting very bravely and strong until the war ended. He lived a happy life after the war was over.

Wednesday, November 27, 2019

What Is The Definition Of Marriage Essays - Marriage,

What Is The Definition Of Marriage? What is the definition of marriage? What is marriage? In Webster's Dictionary marriage is defined as the institution whereby men and women are joined in special kind of social and legal dependence for the purpose of founding and maintaining a family. The definition states ?a man and a woman not a man and a man?. Some people believe same gender marriages should be allowed. But right now the law doesn't allow same gender marriages. I guess only time will tell if that law will ever change. Marriage has always been an evolving institution, bent and shaped by the historical moment and the needs and demands of its participants (Johnson 266). The Romans recognized the phenomenon we call ?falling in love,? but they considered it a hindrance to the establishment of stable households (266). Marriages certified by the state had their foundations not in religion or romance but in pragmatics-e.g., the joining of socially prominent households (266). At the beginning of the thirteenth century, facing schisms and heresies, and seeking to consolidate its power, the Catholic Church institutionalized marriage, confirming it as a sacrament and requring that a priest officiate-a crucial step in the intrusion of organized religion into what had previously been a private transaction (266). So instead of just having any person marry a couple you now have to have a priests officiate the couple. This is another issue that makes a marriage more difficult besides the gender issue. To be an official marriage a couple must have a license and the right person to perform the wedding, like a justice of the peace or a priests. Throughout the U.S. same-gender marriages are illegal. The state of Hawaii tried recently to allow these marriages. However, Congress overwhelmingly passed the Defense of Marriage Act. This act undercut Hawaii's effort and made it practically useless. The Defense of Marriage Act permitted states not to recognize same-gender marriages performed in other states. There is a separation between church and state in this country (Sullivan 260). Andrew Sullivan states ?we are asking only that when the government gives out civil marriage licenses, those of us who are gay should be treated like anybody else? (260). Many people just don't believe marriage should be between two people of the same sex. Throughout history marriage has always been between a man and a woman and that's the way many want to keep it. Many people believe that gay marriage would cause the American family to break down. Others say they are citizens just like you and me and deserve equal rights. Lisa Bennett poses the issue like this: What the people who have the power to rule on same-sex marriage know of a relationship like mine, I cannot say. I know they claim that our marriage would make a mockery of theirs; they warn that our families would cause the decline of the American family; and they label our love immoral, disgusting, even dangerous. The shocking thing is that before I knew what it meant to fall in love with a person of the same sex, I might have agreed with them. But now, having been on both sides of the fence. I know that to understand a life that is different from the life lived by most people takes time-and an open mind.Like everybody else I know I want to get married because I was raised to believe that marriage is how we best honor a lifelong relationship. I want to feel the support from the family and society that marriage brings. And I want people tp know they can not interfere: Love is love, In whatever shape it comes, it deserves respect. Throughout history marriage is believed to be a union between two people. These two people have always been a man and a woman. Not a man and another man, or a woman and another woman. This belief has been challenged in recent years because many people believe it's time for a change. They feel that if you are in love the same gender issue should not matter. It's going to take many more years I believe for the laws to change. People in this day and age just are not ready for same

Sunday, November 24, 2019

Hobbes vs Plato on Justice essays

Hobbes vs Plato on Justice essays Plato on Hobbes view of justice According to Hobbes, justice must be defined as nothing more than abiding by the law. However, from Platos point of view, this notion of justice is not adequate. Regards to human nature, Hobbes is very pessimistic, while Plato is less so. Based on different views on how the society should be formed, Plato gives different accounts of Justice than Hobbes. This difference will become clear once we learn Hobbes reasoning on his definition of Justice as well as Platos opinions on the issues related to that reasoning. To define justice, Hobbes traces down to the nature of human being. In Hobbes view, the nature of human being is selfish and vain. This nature makes people compete with each other, distrust each other and moreover lust for fame. Therefore, in the state of nature, a war of all against all is unavoidable and the life of man is nothing but tragic. To achieve peace, people make a contract all together to lay down their rights over others. This contract could last only when all members of the contract abide by it. It requires a commonwealth to enforce the performance of the covenant. Justice from a functional point of view then comes into being: it is just abiding by the law. If someone breaks the contract, he will be accused as injustice. First, Hobbes asserts that man is just matter in motion. This material man has no interest other than the preservation and promotion of his own existence. The good is what is in his private interest. Typically, Hobbes verifies three principle desires and passions of man: to gain properties, to secure himself and to glean reputation. It is interesting that Hobbes proposes equality of man as regard to the body and mind. His argument for this equality as regard to the body lies in the fact that the weakest has enough power to kill the strongest. As for mind, it is only because of the distance of other mens wits that makes p...

Thursday, November 21, 2019

The Occupation of France through the eyes of Irne Nmirovsky in Suite Dissertation

The Occupation of France through the eyes of Irne Nmirovsky in Suite Franaise - Dissertation Example Irene Nemirovsky’s book, Suite francaise, written in two sections, ‘Storm in June’ and ‘Dolce,’ starts with an air raid siren going off in the early morning hours before sunrise, yet people are still not so anxious as of yet that they feel they must run away (Nemirovsky 3). (Indeed, many went back to sleep for just a bit longer once the sirens stopped.) Yet, in the distance, there was the sound of heavy guns firing, some of it coming closer and closer. Finally, the sun comes up and the shelling stops. There is a peaceful, yet uncertain pause in the craziness. Something is just waiting around the corner, yet to be seen (Nemirovsky 4). In this glimpse of the novel, we are made aware of the fact that people just barely understand what is happening to them and really cannot believe any rumours and reports they have been getting about the German forces moving their way or that things could be that bad (Nemirovsky 5). As is so often seen, when changes are m ade within a society coming from the outside, people do not want to believe that they are in danger. It is a case of pulling the night mask over one’s eyes so as to wake up and find that everything is alright again and back to normal. In fact, in the novel, this is the beginning of the end of whatever normal they had in their lives. It is a down-hill spiral from that point onwards. Suite francaise presents a number of people in all their diverse personalities, set in a time that will turn to a future of unimaginable horror. At the period of time that Irene writes this book, many of the horrors committed by the Nazis are still unknown definitively to most outside of the European theatre of war, but there had been rumours. Indeed, Irene may have suspected or heard through the rumour mill about what was truly happening to the Jews, of which she was one. Most, however, did not want to believe that such things were happening and it would not be until the end of WWII that the truth of the genocide of the Jewish people and other ‘undesirables’ would be fully revealed and even then, some would not believe it did take place. The background in the novel therefore provides a scenario which is perceived by the characters as they would have known their own world for that time when people did not know that much about what was happening, only that there was a war going on. In our current age of the Internet and social media of modern times, information and news travel around the world in a flash, within seconds or even milliseconds. At the beginning of WWII, however, information would have taken far more time to be dispersed to the general population in varying levels of electronic access by radio. Under the German occupation, much of that news would have been restricted and also turned to propaganda before being released to the general public. Therefore, her characters also react accordingly to what they know at that point in time of occurring history, n ot what we know in our perspective of that history many decades later. Regarding these two points of view, we see what is coming for these people but we can only shout silently to deaf ears of the characters in this story because they are not there yet in that level of knowledge. The time we know of through historical documentation, has not yet occurred for them or if it is occurring, they do not know of it yet, while we, who are in the future, already know where the story is headed, at least

Wednesday, November 20, 2019

Negotiation skills - QUESTIONS 2 Essay Example | Topics and Well Written Essays - 1500 words

Negotiation skills - QUESTIONS 2 - Essay Example Avoiding in a conflict situation generally means postponing, showing lack of assertiveness or withdrawing from issues (at present time) in order to deal with them later or in other words showing reluctant behavior in terms of solving problem. However this avoidance may be deliberate in order to come up with the better solution later or for so many reasons (Trainer, 2012, p. 3). Moreover using this technique too much can result in creating a communication gap which further leads towards unhealthy co ordination as both parties are unable to know the stance of each other. Similarly if avoiding is overused it may affect the nature of the decision or stance of the other party. Likewise if avoiding is underused it may result in creating a situation which might hurt individuals feeling as usually discretion is not very much opt by individuals. Furthermore if individual is less likely to follow avoiding policy he is likely to be threatened by various issues and conflicts. Accommodating generally means sacrificing ones interest, goals or motives in order to give preference to others for satisfying their concerns. It can be use for number of reasons for instance if an individual is wrong and feels like correcting himself, or if a boss in a company accommodates employees in order to give them chance so they can learn from their previous mistakes (Trainer, 2012, p. 3). Accommodating if overused can lead towards losing of respect as employees are likely to make mistakes and take employer for granted. Moreover employer may lose his overall control over his employees because of overuse of accommodating factor. However if this factor is underused it may result in creating trouble in so many dimensions, for instance in creating goodwill, realizing, and accepting one’s own mistakes. Compromising is a phase in which both parties understand each other’s point of view and are willing to give up

Sunday, November 17, 2019

The Main Advantages of Sales Force Automation Essay

The Main Advantages of Sales Force Automation - Essay Example Salesforce automation is a component of CRM that is implemented to execute, drive, and track sales initiatives. SFA systems organize sales teams by providing the tools to properly manage leads, accounts, opportunities, and marketing campaigns. (Sales Team Automation) Â  The contemporary age is the era of industrialization and technological advancement. The quick and accurate flow of information regulates the corporate companies within the business environment. All the great organizations are applying latest methods of communication and marketing while making and developing their strategies. Bill Gates, the Chairman of Microsoft Corporation, declares fast flow of information and application of technology to be in leading position. The most meaningful way to differentiate your company from your competitor, the best way to put distance between you and the crowd, is to do an outstanding job with information. How you gather, manage, and use information will determine whether you win or lose. (Gates: 1999 p 1). The managers of sales force apply sales marketing systems, i.e. the information management systems highly supportive in the mechanization of sales force administration; sales force automation is a part of it. Simply put the term refers to the s ystem that could maintain and keep the record of the complete sales process automatically. SFA includes a contact management system which tracks all contact that has been made with a given customer, the purpose of the contact, and any follow up that might be required.

Friday, November 15, 2019

Development of Dynamic Contrast-Enhanced MRI

Development of Dynamic Contrast-Enhanced MRI Ioannis Tolios â€Å"Dynamic Contrast-Enhanced MRI† Introduction One of the most significant non-invasive imaging modalities applied both in research and clinical diagnostics cis Magnetic Resonance Imaging (MRI). Its widespread use is partially based on its characteristic to visualize tissues with high resolutions in 3D and its ability to provide anatomical, functional and metabolic tissue information in vivo (Strijkers, Mulder, van Tilborg, Nicolay, 2007). In an MR image, the basic contrast mostly derives from regional differences in the intrinsic T1, T2 relaxation times, except for local water content differences. T1 and T2 relaxation times can be selected independently to have a commanding influence on image contrast. Nevertheless, a sensitive and accurate diagnosis cannot always be feasible, due to the fact that the intrinsic water, T1 and T2 contrast values are modified and become very often limited by tissue pathology. Consequently, the need for enhanced image contrast led to the growing use of intravenously injected MRI contrast agents, wh ose use although violates partially the non-invasive character of MRI brought about significant benefits. Combining MRI and contrast agents (CA) increases the possibilities to image inflamed tissues in pathologies, such as arthritis, atherosclerotic plaques, and tumor angiogenesis (Strijkers, Mulder, van Tilborg, Nicolay, 2007). Definition of DCE-MRI A technique which combines MRI and contrast agents is Dynamic Contrast-Enhanced MRI (DCE-MRI). According to Gordon et al. (Gordon, et al., 2014), â€Å"DCE-MRI analyzes the temporal enhancement pattern of a tissue following the introduction of a paramagnetic contrast agent into the vascular system. This is accomplished by the acquisition of baseline images without contrast enhancement, succeeded by a set of images acquired over time (usually over a few minutes) during and after the arrival of the contrast agent in the tissue of interest†. A time intensity curve (TIC) for the tissue is generated by the acquired signal, as it can be seen in Figure 1. In a TIC, the response of the tissue is represented in enhancement values to the arrival of the contrast agent. Specific physiological properties that are in association with the microvascular blood flow, including tissue volume fractions, vessel permeability, and vessel surface area product, can be extracted by analyzing a TIC (Gordon, et al., 2014). Figure 1: An example of a time intensity curve obtained from a tumor metastasis (Bonekamp Macura, 2008). All variations of DCE-MRI studies are relied on a rather plain fundamental principle: the MR signal intensity of a tissue is modified, when a paramagnetic particle (contrast agent) penetrates and spreads over through the tissue, based on its local concentration (Gordon, et al., 2014). MR images of a chosen region of interest (ROI) are obtained in time intervals of few seconds before, during, and after the intravenous injection of a contrast agent. Each obtained image represents one time point, and each and every pixel in a set of images produces its own intensity curve. After the injection of the CA, the signal intensity varies at every time point (is related to the concentration of the CA in the tissue) based on tissue parameters, including vascularization, vessels’ permeability and surface area product, and in this way parametric maps of particular microvascular biomarkers can be extracted. Furthermore, by using suitable mathematical models absolute values of the aforementioned parameters can be estimated. These parameters usually reflect a compartmental pharmacokinetics model demonstrated by CAs, which are allocated between the intravascular and extravascular spaces as it can be seen in Figure 2 (Gordon, et al., 2014). Figure 2: Toft’s compartmental model for calculating DCE-MRI quantitative pharmakokinetic parameters (Verma, et al., 2012). DCE-MRI techniques Currently, two DCE-MRI techniques are defined based on its registration and the origin of the extracted signal. As MRI is highly sensitive to small concentrations of paramagnetic materials passing through a tissue, there are two different physical-chemical properties (Gordon, et al., 2014). Relaxation effect T1, T2 tissue relaxation times are reduced when a diffusible contrast agent is used. Positively enhanced T1-weighted images are generated, when this effect is used and the studies evaluating this effect are characterized asDynamic Contrast Enhanced(DCE)-MRI,T1-W DCE. Susceptibility effect When a paramagnetic contrast agent is located in the intravascular space of a tissue and its magnetic susceptibility is much higher than that of the surrounding tissue water, local magnetic inhomogeneities between the intra and extravascular space emerge, which generate negative enhanced T2 or T2* weighted images during the passage of the CA through the capillaries. Studies depending on this phenomenon are characterized asDynamic Susceptibility Contrast(DSC)-MRI or T2*-W DCE. Image Acquisition Gordon et al. (Gordon, et al., 2014) state that the method of quantification to be applied depends on the number of the measurements, which are required in order to obtain the data; thus, the measurements include: I. Creating a map of pre-contrast native T1 values, which is necessary in order to calculate the CA concentrations. II. Acquiring heavily T1-weighted images, prior and following the Contrast Agent introduction. In this case, high temporal resolution is needed in order to have the ability to further characterize the kinetics of the contrast agent’s entry and exit of the tissue. Typically, 3D image sets are acquired sequentially for 5–10 minutes every few seconds. The ideal for the acquisitions would be to be obtained approximately every 5 seconds, in order to allow the detection of early enhancement. With longer acquisitions (for instance, > 15 seconds), it becomes harder to detect early enhancement. III. Acquisition of the arterial input function (AIF), in order to estimate the CA concentration in the blood plasma of a feeding artery as a function of time. Acquiring the AIF is necessary for almost all quantitative analysis methods and is up to now technically the most difficult part in the data acquisition process. Contrast agents The most regularly used group of contrast agents in DCE-MRI is the low molecular paramagnetic gadolinium (Gd) chelates (Gribbestad, Gjesdal, Nilsen, Lundgren, Hjelstuen, Jackson, 2005). Principally, in Dynamic Contrast-Enhanced MRI, any low molecular weight CAs can be used. (Tofts). The use of contrast agents with high molecular weights leads to lower permeability and lower Ktrans values, since these agents remain in the intravascular space. Using macromolecular CAs the measurement of regional blood volume acquiring scans of low temporal resolution is feasible (Gribbestad, Gjesdal, Nilsen, Lundgren, Hjelstuen, Jackson, 2005). Molecular agent with high molecular weight might be more appropriate for tumor angiogenesis and thus offer better response evaluation to therapy (Turkbey, Thomasson, Pang, Bernardo, Choyke, 2010). Analysis Methods Gordon et al. (Gordon, et al., 2014) state that â€Å"the arrival of CA and thus the enhancement pattern of the tissue depend on a wide variety of factors including vascularity, capillary permeability, perfused capillary surface area, volume and composition of extracellular fluid, renal clearance and perfusion. The analysis of DCE data can provide valuable information concerning the vascular status and perfusion†. Data analysis can be performed using either: qualitative, semi-quantitative, and quantitative approach (Verma, et al., 2012). Qualitative This kind of analysis can range from visual inspection of the images for fast and extreme enhancement of lesions, to the plotting of kinetic curves of signal intensity against time (Gupta, Kauffman, Polascik, Taneja, Rosenkrantz, 2013). The qualitative analysis of DCE-MRI depends on the assumption of rapid and intense enhancement and wash-out as indicator of the existence of a tumor. The tumor vessels are generally leakier and more readily enhanced after the injection of the CA than the ordinary vessels. An early rapid high enhancement after injection is expected followed by a relatively rapid decline compared with a slower and continuously increasing signal for normal tissues during the first few minutes after contrast injection. However, the possibility for an overlap between the natural and the malignant tissues, limit the capabilities of this DCE-MRI approach. Finally, the qualitative approach is regarded as a subjective approach and therefore difficult to standardi ze among institutions, constituting multicenter trials less reliable (Verma, et al., 2012). Semi-quantitative – The semi-quantitative approach also depends on the same assumption as the qualitative approach. On the other hand, in the semi-quantitative analysis various curve parameters are integrated (Verma, et al., 2012). It must be mentioned that depending on the application area, different perfusion parameters are relevant. Nevertheless, some parameters are of general interest for almost all applications. These parameters are acquired to characterize the shape of the TIC, including the time of first arrival of the CA, peak enhancement ( PE the maximum value normalized if the baseline is subtracted), time to peak (TTP the timepoint where peak enhancement takes place), integral (the area between the baseline and the curve, indicating with PE if blood supply is reduced in a ROI), mean transit time (MTT – the timepoint where the integral is bisected), slope (the curve’s steepness during wash-in phase, downslope (the descending curve’s steepness i n wash-out phase ) and wash-in and wash-out curve shapes (Figure 1, Figure 3A). (Preim et al., 2009). Three common dynamic curve types exist in the literature after the initial CA uptake: type 1, persistent increase; type 2, plateau; and type 3, wash-out after initial slope, as it can be seen in Figure 3B and Figure 1. Even though the semi-quantitative approach is used widely in the evaluation of DCE-MRI, significant restrictions arise dealing with the factors contributing to the MR signal intensity (e.g. generalization across acquisition protocols, sequences), which have an effect on the curve metrics (Verma, et al., 2012). Figure 3: A) A typical TIC curve (Preim et al., 2009). B) Differentiation of three patterns of washout phase: type 1 (blue), progressive; type 2 (green), plateau ; type 3 (red), wash-out (Verma, et al., 2012). Factors like the injection rate and the temporal resolution can easily alter the shape of a wash-in/washout curve, creating difficulties in comparison and quantitation. High inter-patient variability is also a factor that can make the definition of threshold values more complex for every parameter that could standardize semi-quantitative approach. However, this approach is relatively simple which makes it even more appealing (Verma, et al., 2012). Quantitative The quantitative approach depends on modeling the concentration change of the CA by integrating pharmacokinetic modeling techniques (Gordon, et al., 2014). Several pharmacokinetic models were proposed, such as by Tofts (Tofts), Brix et al. (Brix et al., 1991). Most of them depend on estimating the exchange rate between extracellular space and blood plasma using some transfer rate constants, like Ktrans(forward volume transfer constant) andkep(reverse reflux rate constant between extracellular space and plasma). â€Å"The transfer constant,Ktrans, is equal to the permeability surface area product per unit volume of tissue.Moreover, Ktransdetermines the flux from the intravascular space to the extracellular space; it may principally represent the vascular permeability in a permeability-limited situation (high flow in relation to permeability), or it may represent the blood flow into the tissue in a flow-limited situation (high permeability in relation to flow). Theveis t he extracellular extravascular volume fraction, andkep=Ktrans/ veexpresses the rate constant, describing the efflux of contrast media from the extracellular space back to plasma. Thevpis the fraction of plasma per unit volume of tissue†, according to Verma et al. (Verma, et al., 2012). In quantitative DCE-MRI analysis, a four compartment model is used for â€Å"tissue†: plasma, extracellular space, intracellular space, and renal excretory pathway (Figure 2). This pharmacokinetic model is applied to the CA concentration changes in the artery (AIF) supplying the tissue of interest, and the CA concentration of the tissue. It must also be noted that due to the fact that pharmacokinetic models require concentration values, signal intensity must be converted to T1 values, because MRI signal intensity is not linear with the CA concentration (Verma, et al., 2012). Clinical Applications of DCE-MRI DCE-MRI has been used for the detection and characterization of tumors in the clinical setting. It also makes the monitoring of tumor treatment and the response to conventional chemotherapy and angiogenic therapies feasible by acting as biomarker (Figure 4). Early tumor detection and treatment affects significantly the survival of patients. DCE-MRI is applied increasingly in a wider range of patients with different kind of cancer, including breast, head and prostate cancer. The method’s quantification ability of characteristics of the lesion microvasculature has stimulated the scientists to use the technique for â€Å"in-vivo staging† of tumors. According to early studies in the field, an evident relationship was demonstrated between large and rapid increases in malignant behavior and signal enhancement in tumors located in prostate, breast, and head. Additionally, important overlapping of contrast enhancement patterns has been noticed between malignant and benign tumor s. Growing accuracy and specificity in the recognition of microvascular characterization parameters is expected to further ameliorate lesion characterization (Gribbestad, Gjesdal, Nilsen, Lundgren, Hjelstuen, Jackson, 2005). More specifically regarding prostate cancer detection and localization, DCE-MRI contributes to prostate MRI, succeeding higher specificity and sensitivity than T2-weighted MR imaging, and sextant u ltrasound guided biopsy, methods being used widely for the pre-treatment work up and screening of prostate cancer respectively (Choi, Kim, Kim, 2007; Bonekamp Macura, 2008). It has been proven that the multi-parametric approach has improved significantly the accuracy of prostate MRI and has a great future. In a cancerous tissue, the number of vessels and their permeability are increased in comparison with normal tissues. Moreover, the interstitial space is greater. These factors cause significant increase of contrast enhancement parameters, such as MTT, blood flow, interstitial volume. The aforementioned observations are applicable in prostate cancer, too. As it can be seen in Figure 3B, the red curve could represent a prostate cancer with faster and steeper enhancement and faster wash-out than in normal tissues. Figure 4 a-c (Turkbey, Thomasson, Pang, Bernardo, Choyke, 2010): a) A patient with prostate cancer. The arrow indicates a low signal intensity focus on axial T2W MR image B) Increased enhancement shown by the lesion on axial T1W DCE-MR image C) fusion of color-coded Ktrans Conclusion The determination of functional microvascular parameters by using DCE-MRI might be instrumental in evaluating many vascular diseases. The potential of the technique to assess the severity of illnesses, to non-invasively and in parallel measure multiple relevant parameters, to study the pathophysiology of diseases, seems to be extremely promising. Even though, the method is known for over 20 years it is still considered immature. This has mainly to do with the significant variations in data analysis and acquisition protocols from study to study. Furthermore, the analysis of the pharmacokinetic parameters is a complex task and computationally expensive, due to the existence of plethora of analysis algorithms (Gordon, et al., 2014). DCE-MRI is restricted in organs with physiologic motion, including lungs and liver, and may not be applicable in some specific group of patients, especially those with renal failure and claustrophobia (Turkbey, Thomasson, Pang, Bernardo, Choyke, 2010). However, although the extraction of quantitative pharmacokinetic parameters is more difficult, compartmental model based methods are more robust than the semi-quantitative approaches, and offer deeper understanding of physiology. Finally, they are not potentially based on the scanning technique, the type of scanner, and individual patient variations ( Gordon, et al., 2014).

Tuesday, November 12, 2019

Elementary, Middle and Highschool Boy-Girl Relationship Essay

Is it too soon to talk about boy/girl relationships in elementary school? Of course it is, you say! Well, you may not want to hear about it, or you may choose denial over reality, but the fact remains that children are playing out the cultural role that they are being taught as early as 2nd grade. Therefore, the relationship between boys and girls at every school (Christian and non- Christian) is a topic that needs to be discussed from a Biblical standpoint. Recently I have observed an increase in the level of interaction between some of the boys and girls at the elementary school level with the boyfriend/girlfriend relationship in mind. There have been some phone calls made and notes passed, and yet nothing really serious has happened. Even so, the fallout from this kind of interest and behavior has been clearly seen, as some of the kids are rejecting others, breaking off friendships, and making â€Å"who likes whom† a focus of attention. The pattern becomes more sophisticated as it continues in the middle school years and is in full bloom by the time the children hit high school. I would like to attempt to persuade you that the elementary level of â€Å"who likes whom,† and the middle school level of â€Å"who is going out with whom,† are not simply innocent and cute stages of life through which everyone must go. As informed Christians professing to glorify the Lord in all things, we need to see if any of this behavior brings glory to God and evaluate the effects of it on our kids. A brief look at the teen dating model and its consequences will show that it is the world’s model, not Christ’s, that we are so accustomed to. Dating is more for a boy and a girl than just spending time together. It’s a lifestyle that involves attitudes and values. It’s a heart thing! Matthew 22:37 says, â€Å"And He said to him, ‘You shall love the Lord your God with all your heart, and wit h all your soul, and with all your mind.’† The first love for our kids is to be Jesus. Our Creator’s plan for our lives is really what we should be directing our kids to focus on; the chief end of man is to glorify God by enjoying Him forever! Romantic male-female relationships are designed by God to be special and singular. The world’s model of dating is one in which you try out many opportunities until you find the one that makes you happy. This type of dating results in a pattern of many broken hearts and bad memories – some of which are detrimental to the intimacy intended for marriage later in life. Interestingly, even the non Christian world is beginning to realize that frequent dating is not healthy. The following are excerpts from an article in the September 8, 2005 Wall Street Journal1 that cites two studies not written from a Christian worldview but nonetheless conclude: * Teens who date a lot don’t have a higher likelihood of developing healthy adult relationships. Instead, their romances in their 20s are likely to be more troubled. * Teens who dated only one or a few people, and formed relationships of more than a few weeks, emerged in their 20s with closer and more-trusting romantic ties than those who had more numerous and fleeting dates. * Unmarried teen girls who settled down with just one partner at 16 or 17- and were still unmarried at 21- are more likely to be eventually married by ages 22-25. Many, including Christians and non Christians, think that dating is just part of the teenage experience. However, putting adolescent boys and girls together leads not only to the emotional experiences that often tear at our children’s hearts but also to sexual experimentation. Think back to your teen years: were you told by a boyfriend or girlfriend in your teen years that he/she loved you? Did he/she eventually marry you? Where did that relationship lead? God wants us to act and think differently. These are matters of the heart. Philippians 1:9-10 says, â€Å"And it is my prayer that your love may abound more and more, with knowledge and all discernment, so that you may approve what is excellent, and may be pure and blameless for the day of Christ.† The goal for most kids in boy/girl relationships is that they are primarily interested in what they are going to get out of the relationship. Sometimes popularity, comfort or pleasure is what a teen gains emotionally or physically. That’s not the kind of love that God would have us live out. That’s choosing what feels good for self rather than what is good for others and pleases God. Parents must be honest and Biblically discerning about the real motivation that lies behind the thoughts and actions of our children. Do love and sincerity motivate the boys in these relationships? Matthew 22:39 says, â€Å"And a second is like it, you shall love your neighbor as yourself.† There is a great book on the subject entitled I Kissed Dating Goodbye, written by Joshua Harris. I have little space here, so I will make a few points and urge you to buy the book. The book is about waiting and preparation, and it debunks and rejects the typical idea of dating and applies a Biblical grid to it. You don’t have to agree with all of his points, but it would behoove you to take a good look at them. Josh Harris says, â€Å"Let’s not do what feels good, but instead do what is good.† He encourages us to look at all of the damage caused by typical worldly dating in the lives of teens and to replace that energy and time with a time of focused preparation for all of life, including preparing for the special relationship of marriage. The book challenges our teens to realize they have no business taking another person’s heart if they are not ready to make a lifelong commitment to that person. He says that if you really love someone, you’ll be interested in that special person’s long-term needs rather than your short-term desires. He exhorts the teen to look at the big picture: serving others and glorifying God. That way, the person is positioned to receive God’s best for them. God has something better for a teen than futile worldly dating! I have two lists for you from the Josh Harris book that are without the further explanation that is needed, but due to lack of space, you’ll just have to get the book to learn more. The seven habits of highly defective dating are: 1. Dating leads to intimacy, but not necessarily commitment. 2. Dating tends to skip the â€Å"friendship stage† of the relationship. 3. Dating often mistakes a physical relationship for love. 4. Dating often isolates a couple from other vital relationships. 5. Dating, in many cases, distracts young adults from their primary responsibility of preparing for the future. 6. Dating can cause discontentment with God’s gift of singleness. 7. Dating creates an artificial environment for evaluating another person’s character. If you are like me, you read those and said amen, I’ve done that before and amen, I see that over and over again. Now here is the refreshing Christian view – five important new attitudes: 1. Every relationship is an opportunity to model Christ’s love. 2. My unmarried years are a gift from God. 3. Intimacy is the reward of commitment; I don’t need to pursue a romantic relationship before I am ready for marriage. 4. I cannot â€Å"own† someone outside of marriage. 5. I will avoid situations that could compromise the purity of my body or mind. Some of you won’t agree. Some of you agree but are saying, â€Å"My child would never go for this.† You are absolutely right. If they have been trained by the world to think like a worldling, they will not want to kiss dating goodbye. But, you are the parent, so†¦.. be the parent! I can’t tell you how often parents tell me what their child will or will not do, so that’s what they (the parents) do. We parents have to take a stand for the Lord and teach the tough things that need to be taught! God will honor that. Some of you are happy that you don’t have teens yet, so you think you don’t have to be concerned. Wrong!!!!!! The reason that we are struggling with our teens and worl dly dating and relationship views isbecause of what they have been taught since Kindergarten. How foolish is it of us parents to allow our child to be taught worldly thinking about male/female relationships and then go to God when our child is 16 years old to beg that He will help our child behave like a Christian when he/she is alone! God will not be mocked! Boys must be taught that they are not to get physical with the girls and that, instead, girls are to be honored and respected. Little things such as holding open a door or helping carry something for a girl are proper and good. The children need to be taught that having an opposite sex relationship is something that is for later in life as you get ready for marriage – something that is also extraordinarily special to people and to God. Boys and girls calling each other on the phone (especially in elementary school) is inappropriate in most cases. We need to teach that people are not possessions that you can trade. Instead, we need to teach them to show real love to one another by helping one another to succeed where they are in life (a student) and to honor God. What are our kids being taught through what they see and hear daily? What are they watching on TV? How about the movies? You and I both know that women are often portrayed as sex objects and trophies. What about at home? Dads, do you treat your wife as the queen of the household? Do your kids see you treating her with great care and affection? Do you realize that everything they see is teaching them how to treat their wives one day? Every year of our lives we are learning and recording permanent records in our minds. I played the worldly relationship and dating game when I was young and things may seem to have worked out OK. My wife and I have been married for 27 years and have a great marriage – but there is more to the story than what you see. Frankly, I am ashamed of many things that I have recorded in my memory regarding male/female relationships from many years ago before I was married. I have prayed that God would remove some of those memories, and He has been gracious, but some remain. In God’s purposes, He often allows us to experience and remember things so we can learn from them and pass the lessons on to others. If you went through the same pattern of worldly dating when you were young, you don’t have to pass it on. You can start afresh with your children. By God’s grace, you have the power to go against the tide of our culture and raise up children who are truly happy and bring glory to God. We have great promises from God that He will be faithful if we will trust and obey Him. I hope that this article has given you some food for thought. Better yet, I hope that you have been convinced that boy/girl relationships in the third, fourth, or fifth grade are yet another battleground for the spiritual struggle for our kids’ hearts. In life, the devil is not kept out of your child’s life by locking a door. We must get after him with all we’ve got and then root out the unbiblical thinking in our kids. 1Shellenbarger, Sue (2005) The Case for Going Steady: Studies Say Teen Dating Habits Affect Marriage Skills. Wall Street Journal, 9/8/2005.

Sunday, November 10, 2019

Addressing International Legal and Ethical Issues Simulation Summary Essay

Conducting international business can be a profitable endeavor but requires a lot of tact and strategy. In international business legal issues may arise but must be resolved in order to retain the relationship. This problem includes but is not limited to changes in legislation, clashes of interest, ethical dilemmas, cultural and ethical differences. When entering into an agreement with another country legal agreements must be drafted to protect the company interest. Consideration must be made of the countries culture and ethical differences. The process of sublicensing can be positive for CadMex. However, the process consumes an incredible amount of time and money. Sublicensing could also violate the non-disclosure agreement. Local customs in laws can conflict with in organizations customs in laws when operating abroad. When this occurs the laws that were specified in the contract should prevail unless there is a CIGS (contracts for the international sale of goods) which is been used by default. See more: Experiment on polytropic process Essay When issues arise alternative dispute resolution (ADR) can be used it is a means for resolving disputes between parties outside of the judicial process using one of four techniques mediation, arbitration, negotiation, or collaborative law. Mediation is the use of a neutral party to resolve the dispute between two or more parties. Arbitration is the resolving of a dispute between parties through the use of an agreed upon party. Negotiation is when the parties have a mutual discussion and arrangement of terms of an agreement. Domestic issues are usually easier to resolve then international issues. Domestic issues do not require the same strategy or consideration does international issues. Domestically the laws are the same but international laws vary from country to country. Contract terms must be defined very explicitly. Sensitivity must be developed and exercised to accommodate local cultures and customs. Laws must also be clearly defined as you leaving as they are part of what can lead your business to success or failure. Addressing International Legal and Ethical Issues Simulation Summary Essay * What are the issues involved in resolving legal disputes in international transactions? All contracts that deal with outside countries must be able to have some type of legal implementation (Melvin, 2011). There has to be some type of enforcement on the contract or it may never be resolved. * What are some practical considerations of taking legal action against a foreign business partner based in another country? According to (Melvin 2011); a country can stop all transactions from that business if they file lawsuit on that country. The law of other countries must be taken into consideration when dealing in foreign business. The United States laws are only upheld within the United States borders and may not be respected in a foreign country. Contracts are only binding if they have the backing of the law in whatever county or countries they are made in. See more: Strategic Management Process Essay * What factors could work against CadMex’s decision to grant sublicensing agreements? Sublicensing agreements comes into play when the organization has too many of them and does not fully incorporate sub-paragraphs. This leaves the organization up for lawsuits if any of the contracted workers do something wrong and also makes the main organization fully liable for any damages. Even workers within the sublicensing can sue a business formed within the sublicensing agreement (Melvin, 2011). * When the local customs and laws conflict with the customs and laws of an organization operating abroad, which should prevail? Explain why. Situations should be handles on a one on one basis. Sometimes special considerations need to be taken to accommodate certain employees due to religious beliefs. In such cases the local laws should prevail in order to prevent a costly and drawn out lawsuit with employee unions. Negotiating and coming to an accord amongst the two would be the best option as well as revising company policy to cater to local customs and laws without losing essentials to company policy. * How would you compare the issues in this simulation to the domestic legal issues discussed in your Week One readings? How should companies resolve domestic and international issues differently? The issues in the simulation are faced in the United Stated everyday by many corporations. The Human resource department of each company is designed to handle such problems when and should they arise. Domestic issues are resolved easier than international issues because they are resolved according to the law of the United States. However when in international waters a corporation (even if it is American) must adhere to the laws of the country it is conducting business in. Litigation and alternative dispute resolution options will apply.

Friday, November 8, 2019

Grammar-Checking Software Is Soft on Grammar Errors

Grammar-Checking Software Is Soft on Grammar Errors Grammar-Checking Software Is Soft on Grammar Errors Grammar-Checking Software Is Soft on Grammar Errors By Mark Nichol You want to improve your grammar, but you’re disinclined to invest time and energy to laboriously study print or online resources about sentence construction. You’ve seen ads on the Internet about grammar checkers, and you decide to check them out. How useful is grammar-checking software? After visiting five grammar-checker websites and using (the free versions of) their products, my conclusion is that software is no substitute for wetware (otherwise known as your brain). Here are my brief reports about the software I sampled. Grammarbase.com Grammarbase.com fallaciously flagged â€Å"ought to be† and â€Å"may be† as examples of passive voice a common misunderstanding of the topic. (Passive voice is a backward-facing construction such as â€Å"This sentence was written by me†; â€Å"I wrote this sentence† is the active alternative. Verb form is not the primary issue.) Worse, there were several real grammatical and syntactical errors in the site’s introductory text (which I used as a test sample for this and the other sites); the grammar-checking tool found none of them. GrammarCheck.net When I copied and pasted the sample text into GrammarCheck.net’s tool, it showed the same poor results as Grammarbase.com’s. However, when I clicked on the site’s Advanced Report button, it took me to . . . Grammarly Grammarly found nearly fifty errors (or, more accurately, instances of concern), mostly involving what the site terms â€Å"writing style,† in the introductory text taken from Grammarbase.com. (The free version did not specifically identify the errors.) When I then plugged in the raw, error-laden version of a copyediting test, it found fewer mistakes than revealed in the Grammarbase.com text but gave the test text a lower score. PaperRater PaperRater found no errors in Grammarbase.com’s text and only two in the text for the copyediting test both concerning misuse of hyphens. Spellcheckplus.com Spellcheckplus.com was stymied by the phrase â€Å"not only should the structure of your writing be solid,† reminding me about noun-verb agreement (irrelevant in this case) and by the phrase â€Å"your basic default word processor grammar checker,† alerting me that if by using your I meant â€Å"you are,† it should read you’re (again, irrelevant). However, it advised changing you’ll to â€Å"you will† and noted that a letter space should both precede and follow an ellipsis and that the first two words in â€Å"run on sentences† should be hyphenated all valid but superficial corrections. My tests were not rigorous, and I did not purchase any of this software I merely took a test drive of each company’s freeware trial. However, the only difference I can see between the free and paid versions of these software products is that the paid versions not only flag your errors but also analyze them. The problem is that, whether in simple or advanced mode, these tools missed just about every error that matters in a grammatical review. These tests confirmed my suspicion that grammar-checking software can at best note only the most elementary errors (and sometimes marks valid constructions as mistakes). Grammar is much too complicated and nuanced to trust to technology. If you want to write well, learn to write well. If you want to have your writing reviewed and evaluated, access the brain of another human being. But don’t even think of relying on software. Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the General category, check our popular posts, or choose a related post below:25 Subordinating ConjunctionsFive Spelling Rules for "Silent Final E"The Difference Between "Un-" and "Dis-"

Wednesday, November 6, 2019

Schools of Thought Regarding the Future of America essays

Schools of Thought Regarding the Future of America essays Schools of Thought Regarding the Future of America Three schools of thought appear to dominate considerations regarding the possible future of the United States of America. These include declinism, American exceptionalism, and neoimperialism. Only time can tell which is the most likely outcome. Realistically, and if history is taken into account, it appears that declinism enjoys favor over the other two possibilities when applied to the American situation. According to declinism, all great nations enjoy a period of greatness, after which they decline. This decline can be blamed on many factors, and often the causes include more than one aspect of the political and social fabric of the once great nation. Declinists hold that the same is true of the United States. The terrorist attacks and subsequent international climate in relation to the United States appear to substantiate the declinist view. The United States have become very powerful and this may have led to a paradigm of unmerited confidence in security and other systems that in fact were not up to standard. The ease with which the September 11 attacks occurred seems to substantiate the lack of security systems. Historically also declinism seems to be the norm for once great nations such as Rome and England. American exceptionalism is the contrasting view to declinism. According to this belief, the United States is unique in its strengths, and shares none of the weaknesses of its once great European counterparts. Thus, the United States is not only great in itself, but also offers opportunities for humanity as a whole. According to this view then, the history of England and Rome is not applicable to the United States, because of the latter's unique qualities. One of these unique qualities setting the country apart from its historical counterparts is its religious ...

Sunday, November 3, 2019

Discussion 5 Assignment Example | Topics and Well Written Essays - 750 words

Discussion 5 - Assignment Example He followed the Lebensraum policy, living room, in order to snatch lands outside Germany and let the German people expand their territory (Spielvogel,1988). In chapter seven the leaders of France and Britain met Hitler to discuss his demands of expanding Germany. They granted him control over a part of Czechoslovakia and in return Hitler pledged to leave the other parts of Czechoslovakia. Hitler broke his promise and took the rest of Czechoslovakia and invaded Poland. This caused the start of World War two. This occurred in September 1939 when German troops invaded Poland and Britain and France declared war. Adolf Hitler’s dream of building a German Empire across Central and Eastern Europe could not be established only through Lebensraum. Lebensraum could only be established by waging a war against the Soviet Union. Hitler’s racial ideology required it, hence the conclusion that World War two was Hitler’s war. Asia, Japan and China also were already at war. More than fifty million people lost their lives during the war, including Germans and also non-Germans In chapter eight Germanies continue with the war and Hitler brought Nazi to power. Hitler enforces his new rules with a secret police, the Gestapo. He formed camps which organized the murder of Gypsies, Jews and political opponents. There was also resistance in the war and the home front was preparing adequately for war (Spielvogel, 1988). In chapter nine the Holocaust took place. It refers to the extensive murders Hitler and his Nazis were accountable for. It involved the formation of squads that followed Hitler’s army to murder Jews and those who were not of German descent. Many camps were set up around Europe and several were determined to murder people. In the years 1939 and 1940, the Nazi army was responsible for the deaths of around fourteen million people which included six million European Jewish people. They

Friday, November 1, 2019

Consumer Coffee Consumption Preference in the Netherlands Research Proposal

Consumer Coffee Consumption Preference in the Netherlands - Research Proposal Example On average, the Dutch consume 3.2 cups of coffee per person everyday according to 2006 statistics making them the second largest coffee consumers after Scandinavians, and although the average is 13 percent lower compared to a decade earlier in 1996, the approximate coffee consumption is significantly high compared to other countries (de Bontridder). Coffee is substantially popular beverage in Netherlands, making a study into factors influencing the popularity, consumption, and preferences important especially for marketing groups wishing to segment the market. Compared to other countries, the Netherlands coffee consumption average is second to Scandinavian countries drinking approximately 4.3 cups of coffee per day between 2002 and 2006, with Finland topping the coffee consumption list at 5.4 cups a day (de Bontridder). In the same period, 2002-2006, eastern and southern Europe registered the least coffee consumption, with southern Europeans drinking approximately 1.9 cups per day a factor associated to higher tea consumption and preference. Various reasons exist, influencing people towards coffee consumption in the western countries, with the two primary factors according to Gelder, Buijsse, Tijhuis, et al being the psychoactive stimulation affect of caffeine content in the coffee and improvement of cognitive performance (Gelder et al 226). Most people in the western countries begin their day with a fresh cup of coffee, essentially to be fully awake for the rest of the day, and be able to maintain coherence in thought because coffee stimulates their brains. Notably, the association of coffee and better cognitive functioning is attributed to the caffeine factor, which enters the blood stream and acts as a stimulant causing alertness in body and mind. In a study conducted over a ten-year period assessing whether coffee consumption influences the cognitive decline in elderly men, the researchers identified variables that influence coffee consumption, which included education, height and weight, gender, physical activities, age, and lifestyle with participants from Finland, Italy, and the Netherlands. Considering age as the relevant variable in this discussion, the findings showed that age was inversely associated with the amount of coffee consumed (Gelder et al 228). The highest consumption was more than 4 cups per day, associated with people aged 74.8 years with a deviation of 0.4, which was the youngest group among the elderly participants, while the least consumers were aged 77 years (Gelder et al 230). In the same study, the Dutch came up as the highest consumers, whereby out of the 336 Dutch participants, 202 drank more than three cups per day compared to 77 of the Fin participants. Another study that shows agreement with the study by Gelder and colleagues is by Luciano, Kirk, and Heath et al, investigating the genetic and environmental influences on tea consumption and finding a common relation with those of coffee consumption. The study participants were 1796 Australian identical twins and 2013 non-identical twins aged 16 to 87 years. The study tested the number of cups of coffee and tea the participants took in a day, and the results showed a negative association of age with coffee preferences but a

Wednesday, October 30, 2019

Equity and Trust Essay Example | Topics and Well Written Essays - 2000 words - 1

Equity and Trust - Essay Example In Tinsley v Milligan, the plaintiff Tinsley sought ownership of a jointly owned property2. Tinsley was the legal owner of the property. She had been living with the defendant Milligan, and these two females had contributed monetarily to the acquisition of that property3. Milligan’s contention was that Tinsley was a trustee for both of them. As such, these women had committed a fraud on the Department of Social Security. They had purchased the property, but had retained title to the property in only the name of Tinsley. This stratagem enabled Milligan to claim benefits from the Department of Social Security, as a person without any property to her name4. In this case, the plaintiff contended that ‘he who comes to equity must come with clean hands.’ Consequently, as per her contention, Milligan was precluded from claiming an equitable interest in the property. The House of Lords ruled that as Milligan did not rely on her illegality, she could enforce such interest. Moreover, it was Tinsley who would have to rely on the evidence provided by the illegal purpose5. It was held by the House of Lords that Milligan could claim her equitable beneficial interests in the property. The Law Lords opined that a plaintiff could claim proprietary interests, as long as she did not rely on an illegality to establish the interest6. Thus, equitable interest of this type was to be considered as similar to the immediate rights to possession under the common law. As such, in this case, two women, paid for a property, but placed the property in the name of one of them. This was done in order to claim housing benefits. However, the courts did not allow this fraudulent behaviour to affect the proprietary rights of the woman, whose name had not been indicated as the half owner of the property. All the same, if the plaintiff had attempted to assert her personal right to entitlement, on the basis of unjust enrichment, she could not have succeeded in her claim.

Monday, October 28, 2019

Analysing Result Graphs Essay Example for Free

Analysing Result Graphs Essay This graph shows the range of ages of the people that I surveyed. The majority was split evenly between the 30 40 age group and the 40 50 age group. I asked for this information so I could find out what age group I should target my business at in terms of style atmosphere and advertising to attract the most possible customers. Now I know who my target audience is I can advertise well to attract customers of that age and set an atmosphere and style to suit that age group. This pie chart shows the average amount of times that the person surveyed goes on every year. This information is vital as it is an indicator as to whether the business will have many customers throughout the year. If the chart were to show that people didnt go on many holidays then there would be no point in the business but as the chart shows the majority of people go on at least 2 holidays on average every year indicating the business will be successful. This doughnut chart shows where the ideal location for Cherry Kennels would be for the majority of the people surveyed. This is crucial to get right because it needs to be located where the public find it most convenient and also were business will be more successful from being close to a lot of potential customers. As clearly shown in the chart, the preferred location for Cherry Kennels would be somewhere situated in Brentwood. Therefore this is where I shall set up Cherry Kennels once I have found a suitable place in Brentwood. This bar chart represents how much the people surveyed are willing to pay per night of their cat/dog staying at Cherry Kennels. It is important to get the pricing correct because it needs to be cheap enough to keep the customers happy and attract more customers, but it needs to be expensive enough to make a decent profit. Thats why I asked this question, to see what the majority of people thought was a fair price. The majority of people believe that à ¯Ã‚ ¿Ã‚ ½30 à ¯Ã‚ ¿Ã‚ ½35 is a fair price per night and I see this to be reasonable and enough to make a profit so therefore this is how it shall be priced. This final graph shows how much the people surveyed are willing to pay to have their dog/cat professionally groomed. I asked this question to find out whether there is any point in having the additional grooming parlours if no-one would use it but not only did the majority of people say they would use it but they also chose a reasonable price again to suit them as customers and me looking to make a profit. As the graph shows the majority of people chose à ¯Ã‚ ¿Ã‚ ½20 à ¯Ã‚ ¿Ã‚ ½25 so therefore this is how it shall be priced. Competitors My main local competitor is Ladybird Kennels located in Ingatestone. This is because they to provide boarding kennels for both cats and dogs. Ladybird Kennels aim to provide their guests with an excellent standard of service and care based on over 10 years of experience. As quoted in their Ladybird brochure.  Ladybird kennels is not in a very busy area but is opposite an entrance to a very busy motorway so a lot of people are constantly driving past, this isnt too much of a problem because the front building/reception area is not that appealing from the outside. By locating Cherry Kennels in a busy place such as Brentwood I hope to gain more customers as it is more conveniently placed than having to go out of your way to get to Ladybird Kennels. Cherry Kennels will provide very similar services as Ladybird Kennels apart from the fact that Cherry Kennels will provide the additional professional grooming parlors. Another difference is that Cherry Kennels will be able to hold and take care of a considerable amount of more cats and dogs. Finally Ladybird Kennels has a Discount food shop which is not planned for Cherry Kennels but could be considered.  Ladybird Kennels is very old fashioned and has been around for ten years so the target audience for its services will probably be the same as Cherry Kennels between 30 50 years of age. This is not a problem however as Cherry Kennels will be more modern to suit this age group and up and coming generations so business will continue well.

Saturday, October 26, 2019

A Discussion On Animal Rights :: essays research papers fc

A Discussion on Animal Rights "Life, liberty, and the pursuit of happiness; The Declaration of Independence holds these rights to be self evident and unalienable. In the eighteenth century when these words were written they were called natural rights, today we call them human rights" (McShea 34). The issue of whether or not to grant animal rights such as those that humans retain, is a greatly disputed issue. Philosophers, clergyman, and politicians have argued the point of animal rights for years, but without success. Animal right is an extremely intricate issue that involves the question of animal intelligence, animal activist groups, and the pros and cons of granting animals their rights. Psychologists around the world, who have studied nonhuman primates, argue that these animals possess the capacity to communicate. They go on to explain that a communication barrier is all that separates humans from animals. If they bridged that barrier, then humans could talk with animals. Beatrice and Robert Gardner, two psychologists of the University of Nevada, realized that the pharynx and larynx of the chimpanzee are not suited for human speech. Since chimpanzees are far superior to humans in manual dexterity, the Garners decided to try to teach chimpanzees American Sign Language or Ameslan. The Gardners and others studied these chimpanzees, Washoe, Lucy, and Lana. These three chimpanzees learned to use and could display a working vocabulary of 100 to 200 words. They also distinguished between different grammatical patterns and syntaxes (Sagan 615). Besides distinguishing, the chimpanzees also inventively constructed new words and phrases. For example, when Washoe first saw a duck land on water, she gestured "water bird," which is the same phrase used in English. Washoe invented that gesture for the occasion (Sagan 615). Lucy also displayed her creative mind by signing "candy drink" after tasting a watermelon. The description "candy drink" is essentially the same word form as the English "water melon" (Sagan 615). Another method of bridging the communication gap between humans and animals is by computer. At the Yerkes Regional Primate Research Center in Atlanta, Georgia, researchers teach chimpanzees like Lana a specific computer language called "Yerkish" (Sagan 616). "Yerkish" allows the chimpanzees to talk with the computer by keyboarding in messages. The computer in turn responds appropriately. While Lana types, she monitors her sentences on a computer display and erases those sentences with grammatical errors. At one point while Lana typed an intricate sentence, her trainer mischievously and repeatedly interfered with her typing from a separate console. Lana, who had become aggravated by this, typed, "Please, Tim, leave room." (Sagan 616). People for the Ethical Treatment of Animals, or PETA, is a nonviolent